Nuclear magnetic resonance (NMR) spectroscopy is a powerful tool in the studies of Structural Biology, Proteomics, Metabolomics, Nutrition, Toxicology, Clinical Research Solutions, Functional Genomics, Structure/Activity Relationship, Drug Discovery and Development, Macromolecule Analysis, and Small Molecule Analysis through a number of methods, including relaxation measurements, chemical shift mapping, hydrogen exchange, conformational exchange, transfer NOE, Saturation Transfer Difference(STD), dynamics and 3D or 4D triple resonance NMR experiments. The SCSB NMR Laboratory is located in its own two-story building on the University of Texas Medical Branch campus at Galveston, Texas (building 73 on the campus map). The current instrumentation includes the state-of-the-art high field Bruker Avance III 800MHz (with TCI cryoprobe), 750MHz, and 600 MHz (with QCI cryoprobe) NMR spectrometers, which is capable of various multi-dimensional 1H/2H/13C/15N/31P NMR experiments. The research though NMR laboratory is focusing on NMR methods, Structure determination, Protein dynamics and function, Small molecules and Metabolomics' study. The core research laboratory offers instrumentation, training, software and assistance in designing NMR experiments.